S84P (p.Ser84Pro) variant of SERPINC1 (Antithrombin-III)
S84P (p.Ser84Pro) in SERPINC1 (Antithrombin-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
S84P (p.Ser84Pro) variant details
- p.Ser84Pro
- TOPMed rs1180794147
- gnomAD rs1180794147
- Missense
- Variant Prioritization Score for Impact Estimate 0.726
- REVEL 0.85
- CADD 27.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available