P36S (p.Pro36Ser) variant of SERPINC1 (Antithrombin-III)
P36S (p.Pro36Ser) in SERPINC1 (Antithrombin-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P36S (p.Pro36Ser) variant details
- p.Pro36Ser
- TOPMed rs1173535550
- gnomAD rs1173535550
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.27
- CADD 14.00
- PolyPhen-2 0.13
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available