P6S (p.Pro6Ser) variant of SCN9A (Q15858)
P6S (p.Pro6Ser) in SCN9A (Q15858) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
P6S (p.Pro6Ser) variant details
- p.Pro6Ser
- cosmic curated COSV57626
- Missense
- Variant Prioritization Score for Impact Estimate 0.78
- MetaLR 0.93
- MetaSVM 1.05
- CADD 24.10
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available