G8R (p.Gly8Arg) variant of SCN9A (Q15858)
G8R (p.Gly8Arg) in SCN9A (Q15858) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
G8R (p.Gly8Arg) variant details
- p.Gly8Arg
- ExAC rs769491361
- gnomAD rs769491361
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- MetaLR 0.96
- MetaSVM 1.10
- CADD 25.80
- PolyPhen-2 0.26
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available