E21* (p.Glu21Ter) variant of RPE65 (Retinoid isomerohydrolase)

E21* (p.Glu21Ter) in RPE65 (Retinoid isomerohydrolase) is a protein-truncating change. Clinical records from EBI and UniProt describe it as pathogenic. The record also includes published literature and structural context.

E21* (p.Glu21Ter) variant details