E33K (p.Glu33Lys) variant of RP2 (Protein XRP2)
E33K (p.Glu33Lys) in RP2 (Protein XRP2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
E33K (p.Glu33Lys) variant details
- p.Glu33Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.21
- CADD 22.00
- PolyPhen-2 0.04
- SIFT 0.35
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available