Y5H (p.Tyr5His) variant of ROS1 (P08922)
Y5H (p.Tyr5His) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
Y5H (p.Tyr5His) variant details
- p.Tyr5His
- gnomAD rs1340793753
- Missense
- Variant Prioritization Score for Impact Estimate 0.0837
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.10
- CADD 0.55
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available