V29D (p.Val29Asp) variant of ROS1 (P08922)
V29D (p.Val29Asp) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
V29D (p.Val29Asp) variant details
- p.Val29Asp
- TOPMed rs1776076888
- Missense
- Variant Prioritization Score for Impact Estimate 0.389
- REVEL 0.39
- MetaLR 0.23
- MetaSVM -0.64
- CADD 24.70
- PolyPhen-2 0.51
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available