V24E (p.Val24Glu) variant of ROS1 (P08922)
V24E (p.Val24Glu) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
V24E (p.Val24Glu) variant details
- p.Val24Glu
- TOPMed rs1251827246
- gnomAD rs1251827246
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.18
- MetaLR 0.09
- MetaSVM -0.99
- CADD 15.80
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available