V24A (p.Val24Ala) variant of ROS1 (P08922)
V24A (p.Val24Ala) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V24A (p.Val24Ala) variant details
- p.Val24Ala
- TOPMed rs1251827246
- gnomAD rs1251827246
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.11
- MetaLR 0.05
- MetaSVM -1.07
- CADD 4.36
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available