T49R (p.Thr49Arg) variant of ROS1 (P08922)
T49R (p.Thr49Arg) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
T49R (p.Thr49Arg) variant details
- p.Thr49Arg
- gnomAD rs1347271467
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.05
- MetaLR 0.10
- MetaSVM -1.03
- CADD 19.70
- PolyPhen-2 0.07
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available