Q69E (p.Gln69Glu) variant of ROS1 (P08922)
Q69E (p.Gln69Glu) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
Q69E (p.Gln69Glu) variant details
- p.Gln69Glu
- TOPMed rs1775324534
- gnomAD rs1775324534
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.23
- MetaLR 0.26
- MetaSVM -0.71
- CADD 22.90
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available