Q59P (p.Gln59Pro) variant of ROS1 (P08922)
Q59P (p.Gln59Pro) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
Q59P (p.Gln59Pro) variant details
- p.Gln59Pro
- ExAC rs778854057
- gnomAD rs778854057
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.26
- MetaLR 0.14
- MetaSVM -0.78
- CADD 23.50
- PolyPhen-2 0.28
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available