Q44K (p.Gln44Lys) variant of ROS1 (P08922)
Q44K (p.Gln44Lys) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
Q44K (p.Gln44Lys) variant details
- p.Gln44Lys
- ESP rs376113207
- ExAC rs376113207
- TOPMed rs376113207
- gnomAD rs376113207
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.07
- MetaLR 0.17
- MetaSVM -0.69
- CADD 23.00
- PolyPhen-2 0.07
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available