N71H (p.Asn71His) variant of ROS1 (P08922)
N71H (p.Asn71His) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
N71H (p.Asn71His) variant details
- p.Asn71His
- ExAC rs753306008
- gnomAD rs753306008
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.09
- MetaLR 0.13
- MetaSVM -0.85
- CADD 23.40
- PolyPhen-2 0.14
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available