N3H (p.Asn3His) variant of ROS1 (P08922)
N3H (p.Asn3His) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
N3H (p.Asn3His) variant details
- p.Asn3His
- gnomAD rs1489703242
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.12
- MetaLR 0.16
- MetaSVM -0.79
- CADD 22.40
- PolyPhen-2 0.19
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available