N13S (p.Asn13Ser) variant of ROS1 (P08922)
N13S (p.Asn13Ser) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
N13S (p.Asn13Ser) variant details
- p.Asn13Ser
- rs45606237
- cosmic curated COSV63863
- UniProt VAR 041442
- 1000Genomes rs45606237
- Missense
- Variant Prioritization Score for Impact Estimate 0.086
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.09
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the HGDP:SHE population (allele frequency 0.11)
- Structural context available
- Cited in: Patterns of somatic mutation in human cancer genomes. (PMID 17344846)