L17F (p.Leu17Phe) variant of ROS1 (P08922)
L17F (p.Leu17Phe) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L17F (p.Leu17Phe) variant details
- p.Leu17Phe
- ExAC rs776963776
- gnomAD rs776963776
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.06
- MetaLR 0.13
- MetaSVM -0.97
- CADD 16.30
- PolyPhen-2 0.01
- SIFT 0.67
- Population evidence available
- Structural context available