K10E (p.Lys10Glu) variant of ROS1 (P08922)
K10E (p.Lys10Glu) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
K10E (p.Lys10Glu) variant details
- p.Lys10Glu
- gnomAD rs1387124417
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.12
- MetaLR 0.11
- MetaSVM -0.96
- CADD 7.88
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available