G60* (p.Gly60Ter) variant of ROS1 (P08922)
G60* (p.Gly60Ter) in ROS1 (P08922) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
G60* (p.Gly60Ter) variant details
- p.Gly60Ter
- cosmic curated COSV10087
- TOPMed rs1775326733
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.864
- CADD 41.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available