C27R (p.Cys27Arg) variant of ROS1 (P08922)
C27R (p.Cys27Arg) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
C27R (p.Cys27Arg) variant details
- p.Cys27Arg
- TOPMed rs1776077506
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.34
- MetaLR 0.10
- MetaSVM -1.01
- CADD 19.40
- PolyPhen-2 0.12
- SIFT 0.00
- Population evidence available
- Structural context available