C19R (p.Cys19Arg) variant of ROS1 (P08922)
C19R (p.Cys19Arg) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
C19R (p.Cys19Arg) variant details
- p.Cys19Arg
- gnomAD rs1179507437
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.22
- MetaLR 0.14
- MetaSVM -0.82
- CADD 22.50
- PolyPhen-2 0.22
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available