A99V (p.Ala99Val) variant of ROS1 (P08922)
A99V (p.Ala99Val) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
A99V (p.Ala99Val) variant details
- p.Ala99Val
- cosmic curated COSV63860
- TOPMed rs1226977360
- gnomAD rs1226977360
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.07
- MetaLR 0.14
- MetaSVM -0.86
- CADD 20.90
- PolyPhen-2 0.26
- SIFT 0.00
- Population evidence available
- Structural context available