A15V (p.Ala15Val) variant of ROS1 (P08922)
A15V (p.Ala15Val) in ROS1 (P08922) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
A15V (p.Ala15Val) variant details
- p.Ala15Val
- gnomAD rs1170566188
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.11
- MetaLR 0.07
- MetaSVM -1.06
- CADD 0.18
- PolyPhen-2 0.00
- SIFT 0.67
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available