Y58N (p.Tyr58Asn) variant of RIT1 (GTP-binding protein Rit1)
Y58N (p.Tyr58Asn) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
Y58N (p.Tyr58Asn) variant details
- p.Tyr58Asn
- gnomAD 1-155904796-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.781
- REVEL 0.89
- MetaLR 0.67
- MetaSVM 0.52
- CADD 29.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available