S10N (p.Ser10Asn) variant of RIT1 (GTP-binding protein Rit1)
S10N (p.Ser10Asn) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
S10N (p.Ser10Asn) variant details
- p.Ser10Asn
- Ensembl rs1673577896
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.19
- AlphaMissense 0.12
- MetaLR 0.12
- MetaSVM -1.02
- CADD 18.00
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available