P15R (p.Pro15Arg) variant of RIT1 (GTP-binding protein Rit1)
P15R (p.Pro15Arg) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
P15R (p.Pro15Arg) variant details
- p.Pro15Arg
- gnomAD 1-155910718-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.07
- CADD 17.50
- PolyPhen-2 0.02
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available