P15L (p.Pro15Leu) variant of RIT1 (GTP-binding protein Rit1)
P15L (p.Pro15Leu) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P15L (p.Pro15Leu) variant details
- p.Pro15Leu
- gnomAD rs1271650033
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.09
- CADD 21.20
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available