K59N (p.Lys59Asn) variant of RIT1 (GTP-binding protein Rit1)
K59N (p.Lys59Asn) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
K59N (p.Lys59Asn) variant details
- p.Lys59Asn
- TOPMed rs1673400156
- gnomAD rs1673400156
- Missense
- Variant Prioritization Score for Impact Estimate 0.391
- REVEL 0.44
- MetaLR 0.24
- MetaSVM -0.65
- CADD 23.40
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available