K23R (p.Lys23Arg) variant of RIT1 (GTP-binding protein Rit1)
K23R (p.Lys23Arg) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
K23R (p.Lys23Arg) variant details
- p.Lys23Arg
- gnomAD rs1311275491
- Missense
- Variant Prioritization Score for Impact Estimate 0.661
- REVEL 0.71
- CADD 25.20
- PolyPhen-2 0.31
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available