I60T (p.Ile60Thr) variant of RIT1 (GTP-binding protein Rit1)
I60T (p.Ile60Thr) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
I60T (p.Ile60Thr) variant details
- p.Ile60Thr
- gnomAD 1-155904789-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.19
- MetaLR 0.06
- MetaSVM -1.06
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.60
- Population evidence available
- Structural context available
- Literature evidence available