G31V (p.Gly31Val) variant of RIT1 (GTP-binding protein Rit1)
G31V (p.Gly31Val) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
G31V (p.Gly31Val) variant details
- p.Gly31Val
- TOPMed rs1673576237
- Missense
- Variant Prioritization Score for Impact Estimate 0.734
- REVEL 0.72
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available