G31C (p.Gly31Cys) variant of RIT1 (GTP-binding protein Rit1)
G31C (p.Gly31Cys) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data, published literature, and structural context.
G31C (p.Gly31Cys) variant details
- p.Gly31Cys
- gnomAD 1-155910671-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.711
- REVEL 0.67
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available