G31A (p.Gly31Ala) variant of RIT1 (GTP-binding protein Rit1)
G31A (p.Gly31Ala) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
G31A (p.Gly31Ala) variant details
- p.Gly31Ala
- gnomAD 1-155910670-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.661
- REVEL 0.60
- CADD 24.30
- PolyPhen-2 0.99
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available