F41L (p.Phe41Leu) variant of RIT1 (GTP-binding protein Rit1)
F41L (p.Phe41Leu) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
F41L (p.Phe41Leu) variant details
- p.Phe41Leu
- gnomAD 1-155910490-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.58
- REVEL 0.67
- CADD 23.30
- PolyPhen-2 0.77
- SIFT 0.15
- Population evidence available
- Structural context available
- Literature evidence available