D75G (p.Asp75Gly) variant of RIT1 (GTP-binding protein Rit1)
D75G (p.Asp75Gly) in RIT1 (GTP-binding protein Rit1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data, published literature, and structural context.
D75G (p.Asp75Gly) variant details
- p.Asp75Gly
- gnomAD 1-155904744-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.858
- REVEL 0.95
- MetaLR 0.93
- MetaSVM 1.09
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available