Y87H (p.Tyr87His) variant of REN (Renin)
Y87H (p.Tyr87His) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
Y87H (p.Tyr87His) variant details
- p.Tyr87His
- ExAC rs752956824
- gnomAD rs752956824
- Missense
- Variant Prioritization Score for Impact Estimate 0.641
- REVEL 0.65
- MetaLR 0.56
- MetaSVM 0.45
- CADD 29.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.5e-05)
- Structural context available