Y121H (p.Tyr121His) variant of REN (Renin)
Y121H (p.Tyr121His) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
Y121H (p.Tyr121His) variant details
- p.Tyr121His
- gnomAD rs1170054174
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.15
- MetaLR 0.15
- MetaSVM -0.78
- CADD 23.00
- PolyPhen-2 0.10
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available