V165M (p.Val165Met) variant of REN (Renin)
V165M (p.Val165Met) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
V165M (p.Val165Met) variant details
- p.Val165Met
- TOPMed rs1276829651
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.38
- MetaLR 0.29
- MetaSVM -0.56
- CADD 25.10
- PolyPhen-2 0.89
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available