V112A (p.Val112Ala) variant of REN (Renin)
V112A (p.Val112Ala) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
V112A (p.Val112Ala) variant details
- p.Val112Ala
- TOPMed rs1221956054
- gnomAD rs1221956054
- Missense
- Variant Prioritization Score for Impact Estimate 0.774
- REVEL 0.89
- MetaLR 0.65
- MetaSVM 0.57
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available