T98A (p.Thr98Ala) variant of REN (Renin)
T98A (p.Thr98Ala) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
T98A (p.Thr98Ala) variant details
- p.Thr98Ala
- gnomAD rs1363702826
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.15
- MetaLR 0.17
- MetaSVM -0.93
- CADD 19.40
- PolyPhen-2 0.02
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available