T73N (p.Thr73Asn) variant of REN (Renin)
T73N (p.Thr73Asn) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
T73N (p.Thr73Asn) variant details
- p.Thr73Asn
- ExAC rs768667467
- gnomAD rs768667467
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.11
- MetaLR 0.14
- MetaSVM -0.95
- CADD 19.50
- PolyPhen-2 0.03
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available