T30S (p.Thr30Ser) variant of REN (Renin)
T30S (p.Thr30Ser) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
T30S (p.Thr30Ser) variant details
- p.Thr30Ser
- Ensembl rs1558246947
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.01
- MetaLR 0.09
- MetaSVM -1.03
- CADD 6.23
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available