T29A (p.Thr29Ala) variant of REN (Renin)
T29A (p.Thr29Ala) in REN (Renin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
T29A (p.Thr29Ala) variant details
- p.Thr29Ala
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0704
- REVEL 0.02
- MetaLR 0.09
- MetaSVM -1.02
- CADD 0.22
- PolyPhen-2 0.00
- SIFT 0.78
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available