T28N (p.Thr28Asn) variant of REN (Renin)
T28N (p.Thr28Asn) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
T28N (p.Thr28Asn) variant details
- p.Thr28Asn
- ExAC rs763754855
- TOPMed rs763754855
- gnomAD rs763754855
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.01
- MetaLR 0.08
- MetaSVM -1.05
- CADD 6.51
- PolyPhen-2 0.08
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available