T21N (p.Thr21Asn) variant of REN (Renin)
T21N (p.Thr21Asn) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
T21N (p.Thr21Asn) variant details
- p.Thr21Asn
- TOPMed rs1420333399
- gnomAD rs1420333399
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.03
- MetaLR 0.09
- MetaSVM -1.00
- CADD 10.80
- PolyPhen-2 0.09
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available