T143R (p.Thr143Arg) variant of REN (Renin)
T143R (p.Thr143Arg) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
T143R (p.Thr143Arg) variant details
- p.Thr143Arg
- TOPMed rs1356009355
- gnomAD rs1356009355
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.14
- MetaLR 0.11
- MetaSVM -1.04
- CADD 18.60
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available