S61G (p.Ser61Gly) variant of REN (Renin)
S61G (p.Ser61Gly) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
S61G (p.Ser61Gly) variant details
- p.Ser61Gly
- TOPMed rs1658256884
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.02
- MetaLR 0.09
- MetaSVM -1.03
- CADD 14.80
- PolyPhen-2 0.00
- SIFT 0.59
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available