S115F (p.Ser115Phe) variant of REN (Renin)
S115F (p.Ser115Phe) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S115F (p.Ser115Phe) variant details
- p.Ser115Phe
- TOPMed rs1658242267
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.29
- MetaLR 0.31
- MetaSVM -0.67
- CADD 22.40
- PolyPhen-2 0.91
- SIFT 0.62
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available