R66M (p.Arg66Met) variant of REN (Renin)
R66M (p.Arg66Met) in REN (Renin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
R66M (p.Arg66Met) variant details
- p.Arg66Met
- ExAC rs754493054
- gnomAD rs754493054
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.05
- MetaLR 0.09
- MetaSVM -1.04
- CADD 6.56
- PolyPhen-2 0.03
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available